Compression Care Center was started by Wes and Jeneen Anderson partly because of an everyday frustration. Wes worked in sales and found his legs and feet ached by the end of his busy days. Jeneen had been working in the compression apparel industry for a few years and knew the positive impact compression socks made on her customer's lives. She bought a few pairs for Wes to try and little did she know their lives were about to change. To no surprise to Jeneen, the support socks she bought did the trick. After wearing his new socks for less than a week it became obvious his pain had completely gone away. On top of helping with the leg and foot pain, he found that his socks stayed up all day, this so happened to be a major pet peeve.

Wes and Jeneen were so impressed by it all they decided to do more than tell the world about it; they began selling them too. In 2005, with the news they were pregnant with their first child they took a leap of faith and began selling online through a website they had professionally built.